| 发明名称 | Antibody against carcinoembryonic antigen and uses thereof | ||
| 摘要 | The invention discloses a humanized chimeric monoclonal antibody against carcinoembryonic antigen (CEA), polynucleotides encoding the antibody, expression vectors comprising the polynucleotides, and host cells containing the expression vectors. The invention also discloses uses of the antibody, polynucleotides, vectors and host cells for manufacturing medicaments for diagnosis and/or treatment of tumors. | ||
| 申请公布号 | US9056911(B2) | 申请公布日期 | 2015.06.16 |
| 申请号 | US201113696251 | 申请日期 | 2011.03.16 |
| 申请人 | Shanghai Haikang Pharmaceutical Tech. & Deve. Co., Ltd. | 发明人 | Yang Zhihua;Ran Yuliang |
| 分类号 | C07K16/30;C12N15/00;A61K51/10;A61K39/00 | 主分类号 | C07K16/30 |
| 代理机构 | Sterne, Kessler, Goldstein & Fox, P.L.L.C. | 代理人 | Sterne, Kessler, Goldstein & Fox, P.L.L.C. |
| 主权项 | 1. A chimeric monoclonal antibody, wherein the monoclonal antibody comprises a heavy chain comprising CDR regions in sequence as set forth in SEQ ID NOs: 7-9, and a light chain comprising CDR regions in sequence as set forth in SEQ ID NOs: 10-12, wherein the monoclonal antibody can specifically bind to carcinoembryonic antigen, and wherein the chimeric monoclonal antibody is produced from the cell line deposited as CGMCC No. 3803. | ||
| 地址 | Shanghai CN | ||