发明名称 |
Piridil-n-(1,3,4)-tiadiazol-2-il-benzeno sulfonamidas cíclicas, processos para sua preparação e seu uso como produtos farmacêuticos |
摘要 |
<p>The invention relates to cyclic N-[1,3,4]-thiadiazol-2-yl-benzene sulfonamides and to their physiologically acceptable salts and physiologically functional derivatives showing PPARdelta or PPARdelta and PPARgamma agonist activity. What is described are compounds of the formula I, in which the radicals are as defined, and their physiologically acceptable salts and processes for their preparations. The compounds are suitable for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders as well as of disorders in which insulin resistance is involved and demyelinating and other neurodegenerative disorders of the central and peripheral nervous system.</p> |
申请公布号 |
BRPI0821915(A2) |
申请公布日期 |
2015.06.16 |
申请号 |
BR2008PI21915 |
申请日期 |
2008.12.12 |
申请人 |
SANOFI-AVENTIS |
发明人 |
KARL SCHOENAFINGER;STEFANIE KEIL;MATTHIAS URMANN;HANS MATTER;MAIKE GLIEN;WOLFGANG WENDLER |
分类号 |
C07D417/12;A61K31/4439;A61P3/10;A61P5/50;A61P25/28 |
主分类号 |
C07D417/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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