Conjugado de hidróxipolímero modificado, uso de conjugado de hidroxipolímero modificado, composição para matar tumor, e, métodos para produzir o conjugado de hidroxipolímero modificado e para tratar câncer.

摘要

The present invention is related to a modified hydroxypolymer conjugate, preferably a dextran-guanidine-biphosphonate conjugate for treating not only skeletal tumors i.e. bone metastasis, particularly bone metastasis related to hormone refractory prostate cancer HRPC and breast cancer, but also osteoporosis. A method for producing and using said hydroxypolymer conjugate is also disclosed.