| 发明名称 |
ALTERNATIVE PROCESS FOR THE PURIFICATION OF AN INTERMEDIATE IN THE SYNTHESIS OF NON-IONIC X-RAY CONTRAST AGENTS |
| 摘要 |
Alternative continuous downstream processes for the production of 5-acetamido-N,N'-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide ("Compound A") are described. Compound A is a key intermediate in the production of iodixanol and iohexol, which are two of the biggest commercially available non-ionic x-ray contrast media agents. |
| 申请公布号 |
WO2015082718(A1) |
申请公布日期 |
2015.06.11 |
| 申请号 |
WO2014EP76873 |
申请日期 |
2014.12.08 |
| 申请人 |
GE HEALTHCARE AS |
发明人 |
HAALAND, TORFINN;ASKILDSEN, ARNE;KALLEBERG, RITA, HESKESTAD;SILALAHI, SUMIHAR;FARBROT, ALF, MARTIN;SAANUM, INGER, DAGNY |
| 分类号 |
C07C231/02;C07C231/24;C07C237/46 |
主分类号 |
C07C231/02 |
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