发明名称 |
METHODS AND COMPOSITIONS FOR REGULATING MUSASHI FUNCTION |
摘要 |
The invention generally features compositions and methods for detecting and regulating cell proliferation, potentiation, and differentiation in a population of cells. In particular, compositions and methods are provided for modulating the activity of Musashi proteins. Diagnostic, screening, and therapeutic methods utilizing compositions of the invention are also provided. |
申请公布号 |
US2015159131(A1) |
申请公布日期 |
2015.06.11 |
申请号 |
US201414559514 |
申请日期 |
2014.12.03 |
申请人 |
Board of Trustees of the University of Arkansas |
发明人 |
MacNicol Angus;MacNicol Melanie;Arumugam Karthik |
分类号 |
C12N5/075;G01N33/561;C07K16/18;C12Q1/68 |
主分类号 |
C12N5/075 |
代理机构 |
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代理人 |
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主权项 |
1. An isolated antibody, wherein the antibody specifically binds to an epitope comprising at least 10 amino acids of an antigenic peptide selected from the group consisting of:
a. about amino acids 311-320 of SEQ ID NO:11; b. about amino acids 271-280 of SEQ ID NO:12; c. about amino acids 311-320 of SEQ ID NO:13; d. about amino acids 291-300 of SEQ ID NO:14; e. about amino acids 291-300 of SEQ ID NO:15; and f. about amino acids 351-360 of SEQ ID NO:16. |
地址 |
Little Rock AR US |