发明名称 METHOD FOR ASSESSING SPERMATOGENESIS CORRECTION EFFICACY IN ANIMALS EXPOSED FOR MICROWAVE RADIATION
摘要 FIELD: medicine.SUBSTANCE: testicular germ cells are measured quantitatively. That is ensured by 50-day oral administration of selexen and ascorbic acid into male white rats in doses 1.5 and 500 mg/kg of animal's body weight respectively once a day. 14 days later, administering the selenium-containing biocomplex is accompanied by the 30-minute daily exposure to microwave radiation at 42 GHz (?=7.1 mm) for 30 days. Once the experimental exposures are completed, the corrective properties of the biocomplex as having an effect on the morphofunctional state of epididymal sperm cells are assessing by formula: MFSI=A+B, wherein MFSI is a morphofunctional state index, A is a portion of normal sperm cells in relation to the reference, and B is a portion of moving sperm cells in relation to the reference. If the MFSI value is 1.3 or more, the spermatogenesis correction is considered to be ineffective, while the MFSI value being more than 1.3 shows the effective spermatogenesis correction if exposed to microwave radiation.EFFECT: invention enables assessing the spermatogenesis correction efficacy with underlying administration of the biocorrector.2 tbl, 3 dwg, 3 ex
申请公布号 RU2552924(C1) 申请公布日期 2015.06.10
申请号 RU20140119347 申请日期 2014.05.13
申请人 GOSUDARSTVENNOE BJUDZHETNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "ASTRAKHANSKAJA GOSUDARSTVENNAJA MEDITSINSKAJA AKADEMIJA" MINISTERSTVA ZDRAVOOKHRANENIJA ROSSIJSKOJ FEDERATSII (GBOU VPO AGMA MINZDRAVA ROSSII) 发明人 LOGINOV PAVEL VADIMOVICH;NIKOLAEV ALEKSANDR ARKAD'EVICH
分类号 G01N33/483 主分类号 G01N33/483
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