摘要 |
PROBLEM TO BE SOLVED: To provide a new gene expression method, a protein or polypeptide production method using the new gene expression method, and recombinant Bacillus subtilis used for the methods, especially, to provide a gene expression method and a protein or polypeptide production method using the gene expression method which are more efficient and simpler than the conventional methods, and to provide recombinant Bacillus subtilis used for the methods.SOLUTION: Bacillus subtilis is used as a host, and the recombinant Bacillus subtilis in which the amount of expression of the rocG gene in the genome is controlled according to culture phases is used. The method by which the amount of expressions of a target gene is efficiently controlled is provided. |