PHARMACEUTICAL ANTI-INFECTIVE COMPOSITION FOR INHALATION

摘要

An anti-infective composition for inhalation, containing, at least an effective amount of an antimicrobial aminoglycoside compound or a salt thereof; and an effective amount of a biofilm modifier which is a macrolide compound or salt thereof.

主权项

1. An inhalation composition for the treatment of lung disease caused by biofilm producing bacteria, fungal or viral pathogens, comprising at least:
(a) an antimicrobial aminoglycoside compound or a salt thereof, and (b) a biofilm modifier which is a macrolide selected from the group consisting of azythromycin, clarithromycin and erythromycin; or a pharmaceutical salt thereof or both;said components a) and b) being in an amount sufficient to disrupt said biofilm and treat said disease.