发明名称 |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain |
摘要 |
Compounds of Formula I: or stereoisomers, tautomers, or pharmaceutically acceptable salts, solvates or prodrugs thereof, wherein Ring A, Ring C and X are as defined herein, are inhibitors of TrkA kinase and are useful in the treatment of diseases which can be treated with a TrkA kinase inhibitor such as pain, cancer, inflammation/inflammatory diseases, neurodegenerative diseases, certain infectious diseases, Sjogren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis and pelvic pain syndrome. |
申请公布号 |
AU2013344886(A1) |
申请公布日期 |
2015.06.04 |
申请号 |
AU20130344886 |
申请日期 |
2013.11.13 |
申请人 |
ARRAY BIOPHARMA INC. |
发明人 |
ALLEN, SHELLEY;ANDREWS, STEVEN WADE;BLAKE, JAMES F.;BRANDHUBER, BARBARA J.;HAAS, JULIA;JIANG, YUTONG;KERCHER, TIMOTHY;KOLAKOWSKI, GABRIELLE R.;THOMAS, ALLEN A.;WINSKI, SHANNON L. |
分类号 |
C07D401/14;A61K31/4155;A61K31/416;A61K31/4162;A61P25/00;C07D231/40;C07D231/54;C07D401/12;C07D403/02;C07D403/04;C07D403/14;C07D405/12;C07D405/14;C07D413/12;C07D453/02 |
主分类号 |
C07D401/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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