Microorganism of the Genus Escherichia Having Enhanced L-Tryptophan Productivity and a Method for Producing L-Tryptophan Using the Same

摘要

The present invention relates to microorganisms of Escherichia coli having enhanced L-tryptophan productivity and to a method for producing L-tryptophan using the same. More particularly, the present invention relates to an Escherichia coli variant in which repression and attenuation control of the tryptophan operon is released and accumulation of anthranilate is reduced and thereby enhancing L-tryptophan productivity. The present invention also relates to a method for producing L-tryptophan using the Escherichia coli variant.

主权项

1. A recombinant microorganism of the genus Escherichia having an enhanced L-tryptophan productivity, wherein the recombinant microorganism has been modified to delete part or all of a leader peptide having a nucleotide sequence represented by SEQ ID NO: 2 in an expression regulatory region having a nucleotide sequence represented by SEQ ID NO: 1 on an endogenous tryptophan operon.