发明名称 |
Gene-Expression Profiling with Reduced Numbers of Transcript Measurements |
摘要 |
The present invention provides compositions and methods for making and using a transcriptome-wide gene-expression profiling platform that measures the expression levels of only a select subset of the total number of transcripts. Because gene expression is believed to be highly correlated, direct measurement of a small number (for example, 1,000) of appropriately- selected transcripts allows the expression levels of the remainder to be inferred. The present invention, therefore, has the potential to reduce the cost and increase the throughput of full- transcriptome gene-expression profiling relative to the well-known conventional approaches that require all transcripts to be measured. |
申请公布号 |
SG10201501626S(A) |
申请公布日期 |
2015.05.28 |
申请号 |
SG10201501626S |
申请日期 |
2011.04.06 |
申请人 |
THE BROAD INSTITUTE, INC.;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;DANA-FARBER CANCER INSTITUTE, INC |
发明人 |
JUSTIN LAMB;TODD R GOLUB;ARAVIND SUBRAMANIAN;DAVID D PECK |
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