发明名称 |
METHODS OF DETECTING DNA, RNA AND PROTEIN IN BIOLOGICAL SAMPLES |
摘要 |
Novel methods of probing multiple targets in a biological sample are provide whereby the targets are DNA, RNA and protein. The method comprises subjecting the sample to an in situ hybridization reaction using a labeled nucleic acid probe that binds an RNA target, observing a signal, and optionally removing the signal. The method further comprises an antigen retrieval protocol, observing a signal, removing the signal, and optionally applying a protease treatment to access the sample's DNA targets by subjecting the sample to an in situ hybridization reaction using a labeled nucleic acid probe, observing a signal from the labeled DNA targets, and optionally removing the signal. |
申请公布号 |
EP2875353(A1) |
申请公布日期 |
2015.05.27 |
申请号 |
EP20130739591 |
申请日期 |
2013.07.12 |
申请人 |
GENERAL ELECTRIC COMPANY |
发明人 |
SOOD, ANUP;GAO, WEI;GERDES, MICHAEL, JOHN;GINTY, FIONA MARY;SEPPO, ANTTI, ELJAS;COLLINS, ELIZABETH MARY |
分类号 |
G01N33/53 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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