发明名称 |
Adsorption method for immobilizing the biomolecule and the biocatalysis system using the adsorption method thereof |
摘要 |
A simple, highly efficient, and environmentally friendly method of immobilizing macromolecules, particularly the biomolecules, to a solid carrier and thus forming a bioreactor, including the following steps: (1) providing the biomolecule and a leading molecule, and linking the biomolecule and the leading molecule by microwave to form an adsorbent; (2) providing a porous support material, and mixing the porous support material and the adsorbent to form a mixture; (3) treating the mixture by a vortex process such that the adsorbent being adsorbed and immobilized on the porous support material to form a bioreactor for biological reactions and biocatalysis; and the bioreactor can be further used for constructing a biological reaction system via incorporating a buffer solution and a ligand. |
申请公布号 |
US9040273(B2) |
申请公布日期 |
2015.05.26 |
申请号 |
US201314140298 |
申请日期 |
2013.12.24 |
申请人 |
Chung Yuan Christian University |
发明人 |
Huang Hsi-Ya;Liu Wan-Ling;Lin Chia-Her;Lo Sheng-Han;Singco Tadena Brenda;Yang Chun-Chuen |
分类号 |
C12N11/02;C12N11/06 |
主分类号 |
C12N11/02 |
代理机构 |
Muncy, Geissler, Olds & Lowe, P.C. |
代理人 |
Muncy, Geissler, Olds & Lowe, P.C. |
主权项 |
1. A molecule immobilization method of immobilizing a biomolecule to perform a biocatalysis, comprising the following steps of: providing the biomolecule and a small molecule which leads the biomolecule, and linking the biomolecule and the small molecule by microwave to form an adsorbent;
providing a porous support material, and mixing the porous support material and the adsorbent to form a mixture; and treating the mixture by a vortex process such that the adsorbent being diffused and immobilized on the porous support material to form a bioreactor. |
地址 |
Zhongli, Taoyuan County TW |