| 发明名称 |
METHODS AND DEVICES FOR ULTRASOUND CONTRAST-ASSISTED THERAPY |
| 摘要 |
Various methods of performing ultrasound contrast assisted therapy are provided. One such method includes delivering a plurality of microbubble-based ultrasound contrast agents to a target area and disrupting the microbubble-based ultrasound contrast agents by delivering tone bursts of ultrasound to the target area. The oscillation of the microbubble-based ultrasound contrast agents can be achieved by delivering ultrasound tone bursts of greater than 5 acoustic cycles with a pulse repetition frequency of between 0.01 and 20 Hz, with pressure greater than 0.3 MPa. |
| 申请公布号 |
US2015141817(A1) |
申请公布日期 |
2015.05.21 |
| 申请号 |
US201314409409 |
申请日期 |
2013.06.27 |
| 申请人 |
University of Pittsburgh - Of the Commonwealth System of Higher Education |
发明人 |
Chen Xucai;Wang Jianjun;Pacella John J.;Villanueva Flordeliza S. |
| 分类号 |
A61B8/08;A61M5/00;A61K49/22 |
主分类号 |
A61B8/08 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of performing ultrasound contrast assisted therapy comprising:
delivering a plurality of microbubble-based ultrasound contrast agents to a target area of a subject; and disrupting the microbubble-based ultrasound contrast agents by delivering tone bursts of ultrasound to the target area, wherein the disrupting of the microbubble-based ultrasound contrast agents comprises delivering ultrasound tone bursts of greater than 5 acoustic cycles with at least one of a (1) pulse repetition frequency of between 0.01 and 20 Hz or (2) a pressure amplitude of greater than 0.3 MPa. |
| 地址 |
Pittsburgh PA US |
