发明名称 |
HPLC ANALYSIS OF IMPURITIES IN DIANHYDROGALACTITOL |
摘要 |
An improved analytical method for analysis of dianhydrogalactitol preparations provides a method for determining the purity of dianhydrogalactitol and detecting impurities in preparations of dianhydrogalactitol, as well as identifying any such impurities. The method employs high performance liquid chromatography (HPLC), in particular, HPLC with evaporative light scattering detection (ELSD); the HPLC can be followed by tandem mass spectroscopy. The method can further comprise the step of performing preparative HPLC collection of at least one specific substance peak present in a preparation of dianhydrogalactitol. |
申请公布号 |
WO2015074025(A1) |
申请公布日期 |
2015.05.21 |
申请号 |
WO2014US66087 |
申请日期 |
2014.11.18 |
申请人 |
DEL MAR PHARMACEUTICALS;LU, XIAOYUN;LI, MIKE, TSO-PING |
发明人 |
LU, XIAOYUN;LI, MIKE, TSO-PING |
分类号 |
C07D301/02;C07D303/14;G01N30/22;G01N30/74 |
主分类号 |
C07D301/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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