发明名称 |
Oncolytic adenoviral vectors and methods and uses related thereto |
摘要 |
The present invention relates to the fields of life sciences and medicine. Specifically, the invention relates to cancer therapies. More specifically, the present invention relates to oncolytic adenoviral vectors and cells and pharmaceutical compositions comprising said vectors. The present invention also relates to a use of said vectors in the manufacture of a medicament for treating cancer in a subject and a method of treating cancer in a subject. Furthermore, the present invention relates to methods of producing GM-CSF in a cell and increasing tumor specific immune response in a subject, as well as uses of the oncolytic adenoviral vector of the invention for producing GM-CSF in a cell and increasing tumor specific immune response in a subject. |
申请公布号 |
AU2009332883(B2) |
申请公布日期 |
2015.05.21 |
申请号 |
AU20090332883 |
申请日期 |
2009.12.21 |
申请人 |
ONCOS THERAPEUTICS OY |
发明人 |
HEMMINKI, AKSELI;KANERVA, ANNA;CERULLO, VINCENZO;PESONEN, SARI |
分类号 |
C07K14/535;A61K35/76;C12N15/861 |
主分类号 |
C07K14/535 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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