Obtaining a tissue sample

摘要

Some embodiments of a biopsy system are configured to obtain a sample of tissue from an internal body site, such as a portion of myocardial tissue from a heart chamber wall. The biopsy system may include a catheter device having tissue collection jaws and an inflatable balloon disposed along a distal portion. Also, the biopsy system may include a pressure sensor device to detect the pressure within the heart chamber in which the tissue collection jaws are disposed.

主权项

1. A biopsy system for collecting a sample of heart tissue, comprising:
a catheter device having an elongate body that extends from a proximal portion to a distal portion, the distal portion being deliverable to a targeted heart chamber; tissue collection jaws to obtain a sample of body tissue, the tissue collection jaws being disposed along the distal portion; an inflatable balloon device to maintain position of the distal portion in the targeted heart chamber when the balloon device is expanded to an inflated condition, the balloon device being disposed along the distal portion at a position proximal to the position of said tissue collection jaws when in said inflated condition, and a pressure sensor device to detect a blood pressure proximate to the tissue collection jaws, the pressure sensor device being coupled to the catheter device, wherein the pressure sensor device comprises a pressure transducer disposed along an outer portion of the catheter device, wherein the pressure sensor device comprises a micromanometer device that, when delivered to the targeted heart chamber, is exposed to blood pressure on one side and a reference pressure on the opposite side, and wherein the tissue collection jaws, inflatable balloon, and pressure sensor device are configured to be located within the targeted heart chamber when the distal portion of the catheter device is delivered to the targeted heart chamber.