| 发明名称 |
PROCESS FOR THE SYNTHESIS OF AN INDOLEAMINE 2,3-DIOXYGENASE INHIBITOR |
| 摘要 |
The present application is directed to processes and intermediates for making 4-({2-[(aminosulfonyl)amino]ethyl}amino)-N-(3-bromo-4-fluorophenyl)-N′-hydroxy-1,2,5-oxadiazole-3-carboximidamide, which is an inhibitor of indoleamine 2,3-dioxygenase, useful in the treatment of cancer and other disorders. |
| 申请公布号 |
US2015133674(A1) |
申请公布日期 |
2015.05.14 |
| 申请号 |
US201414535781 |
申请日期 |
2014.11.07 |
| 申请人 |
INCYTE CORPORATION |
发明人 |
Tao Ming;Frietze William;Meloni David J.;Weng Lingkai;Zhou Jiacheng;Pan Yongchun |
| 分类号 |
C07D413/04;C07C307/06;C07D271/04 |
主分类号 |
C07D413/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A process comprising reacting a compound of Formula F5:with an aldehyde of Formula F6:wherein Pg1 is an amino protecting group, to afford a compound of Formula F7: |
| 地址 |
Wilmington DE US |
