发明名称 |
GASTRORETENTIVE SOLID ORAL DOSAGE FORMS WITH SWELLABLE HYDROPHILIC POLYMER |
摘要 |
<p>The disclosure provides multiparticulate systems that give release of active agents with a narrow window of absorption such that there is bioavailability to a patient. The disclosure provides a composition comprising microparticulates comprising a swellable hydrophilic polymer and an active agent, wherein the swellable hydrophilic polymer is substantially non-crosslinked intramolecularly, and the size of the microparticulates is about 500μm or less.</p> |
申请公布号 |
EP2521570(A4) |
申请公布日期 |
2015.05.13 |
申请号 |
EP20100844270 |
申请日期 |
2010.12.28 |
申请人 |
IMPAX LABORATORIES, INC. |
发明人 |
ALANI, LAMAN LYNN;KOU, JIM, H.;CHIN, SHOOK-FONG;DING, GUANGBIN;MASAND, NATASHA, G. |
分类号 |
A61K47/48;A61K9/16;A61K9/22;A61K31/135;A61K31/195;A61K47/30;A61K47/38 |
主分类号 |
A61K47/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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