| 发明名称 |
Ruthenium catalysts and their use for asymmetric reduction of ketones |
| 摘要 |
Disclosed are novel ruthenium compounds of formula (Ia) and (Ib):;
wherein R1 and the moiety are defined herein. Also disclosed is a process for using these novel ruthenium compounds as catalysts for asymmetric hydrogenation and transfer hydrogenation of ketones with high reactivities and excellent selectivities. |
| 申请公布号 |
US9029540(B2) |
申请公布日期 |
2015.05.12 |
| 申请号 |
US201414313085 |
申请日期 |
2014.06.24 |
| 申请人 |
Boehringer Ingelheim International GmbH |
发明人 |
Haddad Nizar;Lee Heewon;Qu Bo;Rodriguez Sonia;Senanayake Chris Hugh |
| 分类号 |
C07F15/00;C07D405/04;B01J31/22;C07D215/20;C07D209/04;C07D333/54;C07D307/79;C07C29/145;C07D231/56;B01J23/46;B01J31/24;C07C29/156;C07B53/00 |
主分类号 |
C07F15/00 |
| 代理机构 |
|
代理人 |
Morris Michael P.;Patel Usha R. |
| 主权项 |
1. A compound of formulae (Ia) and (Ib):wherein R1 are both the same and selected from —H, —CH3 and —OCH3; and the moiety represents a diamine ligand selected from the group consisting of compounds 4, 5, 6, 7, 8, 9, and 12: |
| 地址 |
Ingelheim am Rhein DE |
