主权项 |
1. A method of treatment of a disorder selected from the group consisting of overactive bladder, irritable bowel syndrome, type 2 diabetes, obesity, hyperglycemia, hyperlipemia, motility dysfunction, excessive gastrointestinal secretion, nonspecific diarrhea, triglyceridemia, retinopathy, nephropathy, neuropathy, cataracts, coronary heart diseases, arteriosclerosis, osteoporosis, atherosclerosis, hyperinsulinemia, depression, muscle wasting, urinary incontinence, and wound-healing, comprising the administration, to a patient in need thereof, of a therapeutically effective amount of a compound of structural Formula Ior a pharmaceutically acceptable salt thereof, wherein:
R1-R24 are independently selected from the group consisting of hydrogen and deuterium; and at least one of R1-R24 is deuterium. |