| 发明名称 |
SOLUBILIZED CAPSULE FORMULATION OF 1,1-DIMETHYLETHYL [(1S)-1-{[(2S,4R)-4-(7-CHLORO-4METHOXYISOQUINOLIN-1-YLOXY)-2-({ (1R,2S)-1-[(CYCLOPROPYLSULFONYL)CARBAMOYL]-2-ETHENYLCYCLOPROPYL} CARBAMOYL)PYRROLIDIN-1-YL]CARBONYL}-2,2-DIMETHYLPROPYL]CARBAMATE . |
| 摘要 |
<p>The present disclosure includes various embodiments directed to a solubilized capsule formulation of asunaprevir, 1,1-dimethylethyl [(1S)-1-{[(2S,4R)-4-(7-chloro-4methoxyisoquinolin-1-yloxy)-2-({ (1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl} carbamoyl)pyrr olidin-1-yl]carbonyl}-2,2-dimethylpropyl]carbamate, and to methods including asunaprevir.</p> |
| 申请公布号 |
MX2014013220(A) |
申请公布日期 |
2015.05.11 |
| 申请号 |
MX20140013220 |
申请日期 |
2013.04.30 |
| 申请人 |
BRISTOL-MYERS SQUIBB HOLDINGS IRELAND |
发明人 |
ROBERT KEVIN PERRONE |
| 分类号 |
A61K9/48;A61K31/4709;A61P31/14 |
主分类号 |
A61K9/48 |
| 代理机构 |
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