COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

摘要

There are represented: pyrimidine derivatives of formula (1) and (2), substitutions thereof R1 and R2 are obtaining values R1 = halogen or C1–6 alkyl, R2 = H, values of substitutions: R3, R4, R5, R5', R6, R8, R9, W and variable n are provided in the claims; and pharmaceutically acceptable salts, pharmaceutical compositions on basis thereof, and application therein the cell, tissue system or mammal organism to inhibit anaplastic lymphoma kinase. Table: 1