| 摘要 |
The invention relates to the field of microbiology, specifically to a bacteriophage, polypeptide and a corresponding polynucleotide, a nucleic acid molecule and/or vector and/or cell comprising such polynucleotide, a composition comprising said bacteriophage, polypeptide, polynucleotide, construct, vector and/or cell, preferably for preventing, treating or diagnosing contamination with and/or a condition in an individual related to Salmonella. The invention further relates to an antimicrobial composition for medical use or for use as a food additive or as a disinfectant, or for detecting bacteria, preferably in a diagnostic application, wherein said antimicrobial composition comprises a bacteriophage, polypeptide, corresponding polynucleotide, construct and/or vector and/or cell comprising such polypeptide and/or composition according to the present invention. |
| 主权项 |
1. A composition comprising an isolated bacteriophage belonging to the morphotype group of the Myoviridae, comprising at least one feature selected from the group consisting of:
the genome of the bacteriophage is at least 100 kbp, the genome of the bacteriophage comprises at least one polynucleotide encoding a polypeptide with an amino acid sequence having at least 70% sequence identity with an amino acid sequence selected from the group consisting of SEQ ID NO: 3, 5, 7, 9 and 11, the bacteriophage receptor is Salmonella outer membrane protein C, the bacteriophage can infect and lyse at least one Salmonella species. |
