LIPID NANOCAPSULES COMPRISING A RETINOID, NANODISPERSION AND COMPOSITION CONTAINING THE SAME, PROCESS FOR PREPARING THE SAME AND USE THEREOF IN DERMATOLOGY

摘要

Lipid nanocapsules are described that include at least one irritating active ingredient, and more specifically a retinoid in solubilized form. Also described, are nanodispersions and pharmaceutical compositions including the same and methods of producing the same. The use of the pharmaceutical compositions in the treatment of dermatological pathologies is also described.

主权项

1. A lipid nanocapsule comprising an oily inner phase and a non-polymeric envelope obtained from at least one surfactant chosen from amphiphilic lipids, wherein the nanocapsule comprises at least one retinoid as a dissolved irritant active principle, and in that the nanocapsule does not comprise any organic solvent of alcoholic type.