| 发明名称 |
Derivados de isoxazol-piridina |
| 摘要 |
<p>The present invention is concerned with (1,1-dioxo-1» 6 -thiomorpholin-4-yl)-{6-[3-(4-fluoro-phenyl)-5-methyl-isoxazol-4-ylmethoxy]-pyridin-3-yl}-methanone or a pharmaceutically acceptable salt thereof. The compounds are active on the GABA A ±5 receptor binding site and useful for the treatment of cognitive disorders, such as Alzheimer's disease.</p> |
| 申请公布号 |
BRPI0820112(A2) |
申请公布日期 |
2015.05.05 |
| 申请号 |
BR2008PI20112 |
申请日期 |
2008.11.26 |
| 申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
BERND BUETTELMANN;ROLAND JAKOB-ROETNE;HENNER KNUST;MATTHEW C. LUCAS;ANDREW THOMAS |
| 分类号 |
C07D413/12;A61K31/4439;A61P25/28;C07D413/14;C07D417/14;C07D487/04;C07D491/08;C07D491/10 |
主分类号 |
C07D413/12 |
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