发明名称 分岐型両親媒性ブロックポリマー、それを用いた分子集合体及び薬剤搬送システム
摘要 Provided is a polymeric micelle pharmaceutical preparation that can increase the ratio of contrast at tumor site to background contrast in a short period of time after administration of a lactosome and can suppress the ABC phenomenon so that the lactosome can be administered more than once within a short span. A branched-type amphiphilic block polymer comprising: a multi-branched hydrophilic block comprising sarcosine; and a hydrophobic block comprising polylactic acid. The branched-type amphiphilic block polymer, wherein the number of branches of the hydrophilic block is 3. A molecular assembly comprising the branched-type amphiphilic block polymer. The molecular assembly further comprising a linear type amphiphilic block polymer.
申请公布号 JP5709113(B2) 申请公布日期 2015.04.30
申请号 JP20130521638 申请日期 2012.06.22
申请人 株式会社島津製作所;国立大学法人京都大学 发明人 小関 英一;木村 俊作;牧野 顕
分类号 C08G81/00;A61K9/10;A61K47/34;B82Y5/00;B82Y20/00;B82Y40/00 主分类号 C08G81/00
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