| 发明名称 |
NOVEL DELIVERY SYSTEM FOR ANTICANCER DRUG BASED ON SHORT-CHAIN-
LENGTH POLYHYDROXYALKANOATE NANOPARTICLES |
| 摘要 |
The invention relates to the fabrication of novel and improved delivery system comprising of short-chain-length polyhydroxyalkanoates (scl-PHA) nanoparticles having anticancer drug ellipticine (EPT) encapsulated therein for oral administration. The scl-PHA is synthesized by indigenous bacterial isolate Bacillus cereus FC11 (NCBI GenBank accession number JN593010) using modified GTYN medium. |
| 申请公布号 |
US2015118293(A1) |
申请公布日期 |
2015.04.30 |
| 申请号 |
US201314066899 |
申请日期 |
2013.10.30 |
| 申请人 |
Masood Farha;Chen P.;Yasin Tariq;Hameed Abdul |
发明人 |
Masood Farha;Chen P.;Yasin Tariq;Hameed Abdul |
| 分类号 |
A61K47/34;A61K31/437;A61K9/14;A61K9/48 |
主分类号 |
A61K47/34 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. An oral drug delivery system comprising an anticancer drug ellipticine encapsulated in a nanoparticle matrix of poly-3-hydroxybutyrate-co-8 mol % 3-hydroxyvalerate (PHBV) for use in cancer patients in need for treatment. |
| 地址 |
Islamabad PK |
