SUBSTRATES AND ASSOCIATED METHODS FOR ELUTION OF NUCLEIC ACIDS

摘要

A solid substrate for biological sample storage under dry-state and elution of biomolecules is provided. The dry, solid substrate is coated with saccharides, such as monosaccharides, oligosaccharides, polysaccharides or combinations thereof, and the substrate is comprised of one or more protein denaturing agents impregnated therein under a substantially dry state. A method for elution of biomolecules from biological samples is also provided. The compositions disclosed herein provide for enhanced elution and recovery of biomolecules, such as nucleic acids, from the sample. The sample is disposed on a substrate, dried to a substantially dry state; eluted from the biological sample dried on the substrate by rehydrating the substrate in an elution buffer.

主权项

1. A solid substrate for eluting biomolecules from a biological sample, comprising:
one or more monosaccharides, oligosaccharides, polysaccharides or combinations thereof, and one or more protein denaturing agents impregnated therein under a substantially dry state.