| 发明名称 |
TOPICAL PHARMACEUTICAL COMPOSITIONS OF ANTIBIOTICS AND STEROIDAL ANTI INFLAMMATORY AGENTS |
| 摘要 |
The present invention relates to sterile, storage-stable topically administrable otic pharmaceutical compositions comprising one or more antibiotic(s) and one or more steroidal anti-inflammatory agent(s) and a process for preparation thereof. The topical pharmaceutical composition of the present invention further comprises ionic polymer and pharmaceutically acceptable excipients thereof. The topical pharmaceutical composition of invention is physically stable and can be easily re-suspended. |
| 申请公布号 |
US2015119371(A1) |
申请公布日期 |
2015.04.30 |
| 申请号 |
US201414528124 |
申请日期 |
2014.10.30 |
| 申请人 |
Micro Labs Limited |
发明人 |
KSHIRSAGAR Rajesh;MUNDADE Sachin |
| 分类号 |
A61K9/00;A61K31/573;A61K47/12;A61K47/18;A61K47/02;A61K47/10;A61K31/496;A61K47/38 |
主分类号 |
A61K9/00 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A stable topically administrable otic pharmaceutical suspension composition comprising one or more antibiotic(s), one or more steroidal anti-inflammatory agent(s), one or more ionic polymer(s) and optionally one or more preservative(s), buffering agent(s), tonicity-adjusting agent(s), surfactant(s) and/or chelating agent(s), wherein the composition has an osmolality in the range from 270 to 330 mOsml/kg and a pH in the range of 4 to 4.8. |
| 地址 |
Bangalore IN |
