发明名称 |
Production of stable non-polyadenylated RNAs |
摘要 |
The invention relates in aspects to hybrid RNAs lacking a poly-A tail and nucleic acid vectors for expressing the RNA. The hybrid RNAs in some instances have a 3' terminal stabilizing triple helical structure. Related methods for expressing said RNAs in vivo and in vitro are also disclosed. |
申请公布号 |
AU2013331351(A1) |
申请公布日期 |
2015.04.30 |
申请号 |
AU20130331351 |
申请日期 |
2013.10.16 |
申请人 |
MASSACHUSETTS INSTITUTE OF TECHNOLOGY |
发明人 |
WILUSZ, JEREMY E.;SHARP, PHILLIP A. |
分类号 |
C12N15/113;A61K31/7105;A61K48/00;C12N5/00;C12N5/095;C12N15/11;C12N15/117 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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