发明名称 TREHALOSE-CONTAINING MAMMALIAN CELL SUSPENSION FOR PREVENTION OF PULMONARY EMBOLISM FORMATION
摘要 A mammalian cell suspension prevents pulmonary embolism formation during administration of mammalian cells, such as mammalian stem cells, through a blood vessel, and a preventive agent against pulmonary embolism formation during administration of mammalian cells through a blood vessel. suspending mammalian cells, such as mammalian stem cells, are suspended in a physiological aqueous solution containing trehalose or its derivative, or a salt thereof as an active ingredient to prepare a mammalian cell suspension for preventing pulmonary embolism formation during administration of the mammalian cells through a blood vessel, including the mammalian cells and trehalose or its derivative, or a salt thereof as active ingredients. Examples of the mammalian cells can include pancreatic islet cells, dendritic cells, natural killer cells, alpha/beta T cells, gamma/delta T cells, and cytotoxic T lymphocytes in addition to mammalian stem cells. Preferred mammalian stem cells can include mammalian mesenchymal stem cells and mammalian pluripotent stem cells.
申请公布号 US2015118196(A1) 申请公布日期 2015.04.30
申请号 US201314398321 申请日期 2013.05.02
申请人 OTSUKA PHARMACEUTICAL FACTORY, INC. 发明人 Wada Tamaki;Doi Masako;Kikuchi Takeshi;Kobayashi Eiji
分类号 A61K35/545;A61K35/28;A61K31/7016 主分类号 A61K35/545
代理机构 代理人
主权项
地址 Tokushima JP