DEVELOPMENT, CHARACTERIZATION, AND USE OF AN ANTI-HYPUSINATED eIF5A ANTIBODY TO DIAGNOSE DIABETES

摘要

Provided herein is a comprehensive characterization of a novel polyclonal antibody (IU-88) that specifically recognizes the hypusinated eIF5A. The antibody IU-88 is useful for the investigation of eIF5A biology, for the development of assays recognizing hypusinated eIF5A, and for methods of treating conditions and diseases that involve the activity of hypusinated eIF5A. The antibody was used to determine that the levels of hypusinated eIF5A were elevated in the pancreatic tissues of patients diagnosed with Type 1 or Type 2 Diabetes.

主权项

1. An antibody, comprising:
an anti-hypusinated eIF5A antibody, or a pharmaceutically acceptable salt thereof.