发明名称 ELEVATED BIOMARKER EXPRESSION IN LUNG CANCER PATIENTS RESPONDING TO TREATMENT WITH MUC-1 LIPOPEPTIDE VACCINES
摘要 The invention is directed to the treatment of lung cancer, preferably non-small cell lung cancer (NSCLC) by means of a combination therapy comprising chemo- radiotherapy and vaccination with muc-1 lipopeptides, preferably tecemotide (L-BLP- 25). The invention relates, above all, to specific biomarkers which are overexpressed and released into the peripheral blood of patients suffering from lung cancer, preferably NSLC, who respond to the vaccination treatment with said drug in combination with chemo-radiotherapy, preferably concurrent chemo-radiotherapy prior to vaccination, compared to respective patients who do not respond or do weakly respond to said treatment.
申请公布号 WO2015058831(A1) 申请公布日期 2015.04.30
申请号 WO2014EP02677 申请日期 2014.10.01
申请人 MERCK PATENT GMBH 发明人 SCHROEDER, ANDREAS;HELWIG, CHRISTOPH
分类号 G01N33/574;G01N33/68 主分类号 G01N33/574
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