发明名称 |
Certain amino-pyrimidines, compositions thereof, and methods for their use |
摘要 |
Provided are compounds of Formula I:;
or a pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, X and m are as defined herein.
;Also provided is a pharmaceutically acceptable composition comprising a compound of Formula I, or a pharmaceutically acceptable salt thereof.;Also provided are methods of using a compound of Formula I, or a pharmaceutically acceptable salt thereof. |
申请公布号 |
US9018223(B2) |
申请公布日期 |
2015.04.28 |
申请号 |
US201414220252 |
申请日期 |
2014.03.20 |
申请人 |
Cytokinetics, Inc. |
发明人 |
Warrington Jeffrey;Bergnes Gustave;Morgan Bradley P.;Chuang Chihyuan |
分类号 |
A61K31/505;A61K31/506;C07D401/14;A61K9/00;C07D239/42;C07D239/48;C07D401/04;C07D401/12;C07D409/14;C07D413/14;C07D417/14;C07D471/04;C07D495/04;C07D513/04;C07D403/10 |
主分类号 |
A61K31/505 |
代理机构 |
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代理人 |
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主权项 |
1. A compound that is 1-(2-((3-fluoro-1-(3-fluoropyridin-2-yl)cyclobutyl)methylamino)pyrimidin-5-yl)-1H-pyrrole-3-carboxamide, or a pharmaceutically acceptable salt thereof. |
地址 |
South San Francisco CA US |