Method to use gene expression to determine likelihood of clinical outcome of renal cancer

摘要

Disclosed is a method for determining a likelihood of recurrence of renal cell carcinoma for a patient with renal cell carcinoma comprising: (a) measuring in a renal cell carcinoma sample obtained from the patient, a level of an RNA transcript of APOLD1, or its expression product; (b) normalising the level of the RNA transcript of APOLD1, or its expression product to obtain a normalised APOLD1 expression level; and (c) determining a likelihood of recurrence of renal cell carcinoma for the patient based on the normalised APOLD1 expression level, wherein increased normalised APOLD1 expression level is negatively correlated with likelihood of recurrence of renal cell carcinoma.