| 发明名称 |
KETOL-ACID REDUCTOISOMERASE USING NADH |
| 摘要 |
Methods for the evolution of NADPH specific ketol-acid reductoisomerase enzymes to acquire NADH specificity are provided. Specific mutant ketol-acid reductoisomerase enzymes isolated from Pseudomonas that have undergone co-factor switching to utilize NADH are described. |
| 申请公布号 |
US2015111269(A1) |
申请公布日期 |
2015.04.23 |
| 申请号 |
US201414581898 |
申请日期 |
2014.12.23 |
| 申请人 |
BUTAMAX ADVANCED BIOFUELS LLC |
发明人 |
LI Yougen;LIAO Der-Ing;NELSON Mark J.;OKEEFE Daniel P. |
| 分类号 |
C12N9/04;C12N15/10;C12Q1/26;C12P7/16 |
主分类号 |
C12N9/04 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A mutant ketol-acid reductoisomerase enzyme comprising the amino acid sequence as set forth in SEQ ID NO: 29. |
| 地址 |
Wilmington DE US |
