The invention relates to engineering of acetyl-CoA metabolism in yeast and in particular to production of acetyl-CoA in a non-ethanol producing yeast lacking endogenous gene(s) encoding pyruvate decarboxylase and comprising a heterologous pathway for synthesis of cytosolic acetyl-CoA.
申请公布号
WO2015057154(A2)
申请公布日期
2015.04.23
申请号
WO2014SE51228
申请日期
2014.10.17
申请人
BIOPETROLIA AB
发明人
NIELSEN, JENS;SIEWERS, VERENA;KRIVORUCHKO, ANASTASIA;ZHANG, YIMING;ZHOU, YONGJIN;BUIJS, NICOLAAS A. A.;DAI, ZONGJIE