发明名称 Use of cyclopamine in the treatment of basal cell carcinoma and other tumors
摘要 The invention relates to a medicament for treatment of a patient having a tumor wherein Hedgehog/Smoothened signaling is utilized for prevention of apoptosis of tumor cells, comprising cyclopamine or another molecule that selectively inhibits Hedgehog/Smoothened signaling, wherein cyclopamine or said another molecule is in an amount adequate for a dosing that induces apoptosis of the tumor cells in the patient and causes decrease of size or disappearance of the tumor.
申请公布号 EP2862570(A1) 申请公布日期 2015.04.22
申请号 EP20140196071 申请日期 2001.07.02
申请人 TAS, SINAN 发明人 TAS, SINAN
分类号 A61K8/96;A61K31/4355;A61K8/06;A61K8/14;A61K8/63;A61K8/97;A61K31/58;A61K36/00;A61K36/896;A61P17/06;A61P35/00;A61P43/00;A61Q19/00;C07J69/00 主分类号 A61K8/96
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