| 发明名称 | Compounds and methods of making compounds | ||
| 摘要 | Embodiments of the present disclosure provide for compounds and methods of making compounds such as those shown in FIGS. 1.1A and 1.1B having formula 2, 3, 4, 5, 11, and 12 and formula 2′, 4′, and 11′, as well as uses for the compounds for imaging, and the like. | ||
| 申请公布号 | US9011817(B2) | 申请公布日期 | 2015.04.21 |
| 申请号 | US201012875339 | 申请日期 | 2010.09.03 |
| 申请人 | The Board of Trustees of the Leland Stanford Junior University | 发明人 | Namavari Mohammad;Gambhir Sanjiv Sam;Mitchell Beverly S. |
| 分类号 | A61K51/00;A61M36/14;C07H19/16 | 主分类号 | A61K51/00 |
| 代理机构 | Thomas|Horstemeyer, LLP | 代理人 | Thomas|Horstemeyer, LLP |
| 主权项 | 1. A method of making a labeled compound, comprising: reacting a compound including an isotope (Ist) with a compound having formula 1′,to form a compound having formula 2′,and conducting deprotection on the compound having formula 2′ to form a compound having formula 3, wherein PG is a protecting group and LG is a leaving group, and wherein R is a compound having a formula selected from the group consisting of R1, R2, R3, R4, R5, and R6:and wherein R′ is a compound having a formula selected from the group consisting of R′1, R′2, R′3, R′4, and R′5, wherein Ac is an acetyl group, and Bz is a benzoyl group: | ||
| 地址 | Palo Alto CA US | ||