Microfluidic system including a bubble valve for regulating fluid flow through a microchannel

摘要

A microfluidic system includes a bubble valve for regulating fluid flow through a microchannel. The bubble valve includes a fluid meniscus interfacing the microchannel interior and an actuator for deflecting the membrane into the microchannel interior to regulate fluid flow. The actuator generates a gas bubble in a liquid in the microchannel when a sufficient pressure is generated on the membrane.

主权项

1. A method for facilitating analysis or processing of a sample, the method comprising:
flowing a sample through a microfluidic flow channel formed in a substrate; propagating a pressure pulse across the microfluidic flow channel in a crosswise direction; and dampening or absorbing the pressure pulse using a first reservoir in fluid communication with the microfluidic flow channel, wherein the pressure pulse is used to sort one or more particles suspended within the sample.