| 摘要 |
Methods, devices and systems are described for treating venous insufficiency in which the vein is compressed at least partially along a treatment zone. A system can be provided including an injection device, such as a glue gun, that is operably connected to a delivery catheter that can be advanced across a treatment zone in the vein. The delivery catheter can be used to deliver one, two, or more boluses of media (e.g., cyanoacrylate) to occlude the vein along different spaced-apart sections of the treatment zone. External compression can also be applied to the vein by a compression element, such as a hand or multifunctional ultrasound transducer, to occlude portions of the vein along the treatment zone prior to or during the introduction of the boluses of media. |
| 主权项 |
1. A system for treating a vein, comprising:
a catheter comprising a proximal opening, a distal opening, and a sidewall, the catheter configured to deliver a vein-occluding substance within the vein, the catheter having a length sufficient to extend from a distal superficial leg vein to a superficial femoral vein junction; a sheath configured to house the catheter at least partially therethrough, the sheath having a length of from about 25 cm to about 100 cm and an inside diameter of from about 3 French to about 7 French; a luer lock configured to mate with the catheter at the proximal opening of the catheter; and an injector carrying the vein-occluding substance, the injector operably connectable to the catheter and comprising a control, wherein actuation of the control causes injection of a predetermined volume of vein-occluding substance, wherein the predetermined volume of vein-occluding substance is between about 0.05 mL and 0.5 mL, wherein the injector comprises a removable chamber having a proximal end and a distal end configured to connect with the luer lock, the removable chamber further comprising a circumferentially enclosed lumen, the injector further comprising a movable wall, and an actuator configured to move the movable wall within the circumferentially enclosed lumen a predetermined distance upon activation of the control, the injector configured to deliver a plurality of spaced-apart boluses of the vein-occluding substance when the actuator moves the movable wall a predetermined distance, thereby expelling a bolus of vein-occluding substance from the chamber, wherein the distal end of the removable chamber forms the distal end of the injector. |
