| 发明名称 |
Compositions and Methods for the Therapy and Diagnosis of Influenza |
| 摘要 |
The present invention provides compositions, vaccines, and methods for diagnosing, treating, and preventing influenza infection using a combination of antibodies raised against the influenza hemagglutinin and the matrix 2 ectodomain polypeptides. |
| 申请公布号 |
US2015104459(A1) |
申请公布日期 |
2015.04.16 |
| 申请号 |
US201414578777 |
申请日期 |
2014.12.22 |
| 申请人 |
Theraclone Sciences, Inc. |
发明人 |
Grandea, III Andres G.;King Gordon;Cox Thomas C.;Olsen Ole;Mitcham Jennifer;Moyle Matthew;Hammond Phil |
| 分类号 |
C07K16/10;A61K45/06;G01N33/543;A61K39/42 |
主分类号 |
C07K16/10 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A composition comprising:
(a) an isolated human antibody or antigen-binding fragment thereof that specifically binds to an epitope of the hemagglutinin (HA) glycoprotein of an influenza virus; and (b) an isolated human monoclonal antibody or antigen-binding fragment thereof that specifically binds to an epitope in the extracellular domain of the matrix 2 ectodomain (M2e) polypeptide of an influenza virus. |
| 地址 |
Seattle WA US |
