| 摘要 |
The invention discloses a method for cleaning or sanitization of an affinity chromatography matrix, comprising the steps of: a) providing an affinity chromatography matrix having oxidation-tolerant proteinaceous ligands coupled to a support, b) contacting the matrix with a sanitization solution comprising at least one oxidant defined by formula I, R –O –O –H (I) wherein R is hydrogen or an acyl group R'-C(O)-, with R' being a hydrogen or a methyl, ethyl or propyl group. |
