Tissue engineered nucleus pulposus replacement

摘要

A nucleus pulposus replacement is described that includes a containment balloon that can sequester synthetic and/or tissue engineered fill material(s) in the nucleus pulposus region of the IVD thus mitigating migration and expulsion of the fill materials. The containment balloon can be formed of a biocompatible material that includes the structural proteins elastin and collagen. The containment balloon is joined to a closure device that can be used to deliver a fill material, e.g., a hydrogel, to the interior of the containment balloon following implantation of the replacement device in the intervertebral disc area.

主权项

1. A nucleus pulposus replacement comprising:
a containment balloon, the containment balloon comprising multiple layered sheets, each of which including elastin and collagen; and a closure device, the closure device being joined to the containment balloon, the closure device including a one-way port for furnishing a fill material to an interior of the containment balloon.