Composition and methods for modulating cell proliferation and cell death

摘要

Described herein are compositions and methods for modulation of p53-dependent cell death and cell proliferation. The compositions are microRNAs and associated nucleic acids.

主权项

1. A method of treating a cancer associated with the p53 gene in a subject, comprising administering to a subject in need thereof an effective amount of a composition comprising a nucleic acid, wherein the nucleic acid comprises SEQ ID NO: 1or a sequence at least about 80% identical to SEQ ID NO: 1.