| 发明名称 | Shelf stable pharmaceutical depot | ||
| 摘要 | A pharmaceutical depot includes a biodegradable polymer having a glass transition temperature of 20 degrees centigrade or less and at least 25% wt solid particles suspended in the biodegradable polymer. The pharmaceutical depot also includes a post-operative pain relieving therapeutic agent. | ||
| 申请公布号 | US9005634(B2) | 申请公布日期 | 2015.04.14 |
| 申请号 | US201113282532 | 申请日期 | 2011.10.27 |
| 申请人 | Medtronic, Inc. | 发明人 | McDonald Phillip E.;Lyu Suping |
| 分类号 | A61K9/14;A61K9/00;A61K47/10;A61K47/32;A61K47/38;A61K9/70;A61K31/4168;A61K31/445 | 主分类号 | A61K9/14 |
| 代理机构 | Sorell Lenna & Schmidt LLP | 代理人 | Sorell Lenna & Schmidt LLP |
| 主权项 | 1. A pharmaceutical depot comprising: a biodegradable polymer having a glass transition temperature of 20 degrees centigrade or less, the biodegradable polymer comprising poly(D,L-lactide-co-glycolide) thereof; solid particles of mannitol in an amount of at least 40% by weight suspended in the biodegradable polymer, the solid particles have a particle size in a range from 50 to 100 micrometers and the pharmaceutical depot comprises methoxypoly(ethylene glycol); and a post-operative pain relieving therapeutic agent in an amount of between 0.01 and 10% by weight. | ||
| 地址 | Minneapolis MN US | ||