System, devices, and methods including actively-controllable sterilizing excitation delivery implants

摘要

Systems, devices, methods, and compositions are described for providing an actively-controllable disinfecting implantable device configured to, for example, treat or prevent an infection in a biological subject.

主权项

1. An implantable device, comprising:
an actively-controllable excitation component configured to deliver a pulsed thermal sterilizing stimulus, in vivo, to a region proximate a surface of the implantable device; at least one scaffold-forming material reservoir including one or more controllable-release ports operable to deliver a scaffold-forming material from the at least one scaffold-forming material reservoir to a region proximate a surface of the implantable device; a control means operably coupled to the actively-controllable excitation component and configured to regulate at least one of a delivery regimen parameter, a spaced-apart delivery pattern parameter, and a temporal delivery pattern parameter associated with the delivery of the pulsed thermal sterilizing stimulus; and a control means configured to control at least one component associated with delivery of the scaffold-forming material from the at least one scaffold-forming material reservoir to a region proximate a surface of the implantable device.