| 摘要 |
FIELD: medicine.SUBSTANCE: if observing clinical risk factors of thromboembolia of the pulmonary artery, venous blood 3 ml is taken from the patient to analyse polymorphisms -174 G>C of IL-6 gene and -308 G>A of TNFalpha gene by polymerase chain reaction. The genetic typing results are determined by assigning certain points: if observing GG genotype of IL-6 gene, 3 points are assigned, GC - 1 point, CC - 0 points; the GG genotype of TNFalpha gene, 3 points are assigned, GA - 1 point, AA - 0 points, the total score of certain patient is derived. If the total score is 4 and more, the presence of individual predisposition to thromboembolia of the pulmonary artery is stated.EFFECT: invention provides the effective assessment of genetic predisposition to thromboembolia of the pulmonary artery.2 tbl, 2 ex |
