发明名称 SORAFENIB ANALOGS AND USES THEREOF
摘要 <p>The present invention provides, inter alia, compounds according to formula I. Also provided are pharmaceutical compositions and kits containing such compounds. Methods for using such compounds, compositions, and kits for treating a subject having system xc-, dysregulation for activating ferroptosis, for inhibiting system xc- in a cell, and for monitoring treatment of a subject having system xc- dysregulation are provided as well.</p>
申请公布号 WO2015051149(A1) 申请公布日期 2015.04.09
申请号 WO2014US58869 申请日期 2014.10.02
申请人 THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 发明人 STOCKWELL, BRENT R.;DIXON, SCOTT J.;SKOUTA, RACHID
分类号 A61K31/17;A61K31/435 主分类号 A61K31/17
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